Human growth hormone (hGH), also known as somatotropin or somatropin, is a peptide hormone that stimulates growth and differentiation of target tissues. Exogenously administered hGH can be an effective treatment for growth disorders in both children and adults. It also is useful in treating catabolic disorders such as muscle wasting associated with acquired immunodeficiency syndrome […]
The Glucagon-Like Peptide 1 Receptor (GLP-1R), a member of Class B family of G-protein coupled receptors (GPCRs), is an effective target for the treatment of type-2 diabetes, and its incretin peptide and varied peptide mimetics are adopted drugs. Despite remarkable anti-diabetic effects, GLP-1R peptide-based agonists are limited by several disadvantages. Although considerable progress has been […]
A useful synthetic tool for any company / laboratory pursuing the synthesis of benzoxaborole-containing targets.
Lead University of the Sciences Inventor Clyde M. Ofner III, Ph.D Unmet Need A major challenge in cancer chemotherapy is the selective delivery of small molecule anti-cancer agents to cancer cells. Doxorubicin (DOX) is a potent antineoplastic agent that is effective against a wide range of solid tumors and lymphomas but it is also associated […]
A Drug Therapy Utilizing the Alpha4 / Beta2 Receptor Target for the Treatment of Obsessive-Compulsive