Lankenau Institute for Medical Research scientists have developed a radically new approach to eradicate topical infections by weakening the local ecology of the infection that supports it. Specifically, they have developed topical over-the-counter (OTC) formulations of safe and effective agents that are capable of clearing recalcitrant topical infections such as onychomycosis, Staph, or plantar wart. […]
Life Sciences
Rheumatoid arthritis (RA) is a chronic autoimmune disease that occurs when the body’s immune system attacks joints, creating debilitating inflammation and pain. Left unchecked this inflammatory condition can permanently damage joint structures, and in some cases, damage the cardiovascular and respiratory systems. This systemic disease affects more than 1.5 million Americans and about 1% of […]
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness and visual impairment in the world. It strikes mostly people age 60 or older. AMD causes an irreversible destruction of the macula, the part of the retina responsible for vision, thereby leading to vision loss. LIMR technology specifically address the wet form of AMD […]
Assays to measure cell growth and survival assays used in the laboratory have many widely known practical and technical limitations, including non-linearity, high background and cumbersome protocols. In particular, commonly used assays using tetrazolium salts to generate a colored product lack sensitivity and accuracy due to reliance on mitochondrial bioreduction and other factors. The market […]
LIMR researchers have developed a fast, accurate and inexpensive assay, the ThiOX test, that measures the overall thiol redox status of any biological specimen. ThiOX addresses the need for a rapid test to monitor thiol oxidative stress in live cells and tissues. The stability of free thiol groups and disulfide bonds (dithiols) in proteins is […]