Age-related macular degeneration (AMD) is the leading cause of irreversible blindness and visual impairment in the world. It strikes mostly people age 60 or older. AMD causes an irreversible destruction of the macula, the part of the retina responsible for vision, thereby leading to vision loss. LIMR technology specifically address the wet form of AMD […]
Life Sciences
Assays to measure cell growth and survival assays used in the laboratory have many widely known practical and technical limitations, including non-linearity, high background and cumbersome protocols. In particular, commonly used assays using tetrazolium salts to generate a colored product lack sensitivity and accuracy due to reliance on mitochondrial bioreduction and other factors. The market […]
LIMR researchers have developed a fast, accurate and inexpensive assay, the ThiOX test, that measures the overall thiol redox status of any biological specimen. ThiOX addresses the need for a rapid test to monitor thiol oxidative stress in live cells and tissues. The stability of free thiol groups and disulfide bonds (dithiols) in proteins is […]
Braftide is a synthetic peptide inhibitor that works via a novel dual mechanism of action to inhibit BRAF, a protein that is responsible for cell proliferation, differentiation, and migration. This protein is an integral part of the MAP kinase / ERK signaling pathway. Mutations in BRAF have been identified in melanoma, colorectal cancer, non-Hodgkins lymphoma, […]
The University of the Sciences research team has uncovered CAPER as a novel therapeutic target inside breast cancer cells. CAPER has been shown to be overexpressed in these cancer cells and seems to be helping the cancer thrive and survive. Targeted cancer therapy is becoming a leading approach to cancer treatment and Dr. Jasmin and […]