Background Multispecific antibodies represent a paradigm shift in biotherapeutics, moving beyond the traditional “one target, one antibody” model of monoclonal antibodies (mAbs). By enabling a single therapeutic molecule to bind two or more distinct antigens or epitopes, multispecific antibodies can engage complex biological networks with a level of precision unattainable by monospecific mAbs. Among these, […]
Drug Manufacturing
Unmet Need The inventors believe this invention may address two areas of unmet need. Growth hormone Deficiency: Long-acting dosage form for recombinant human growth hormone (r-hGH) is currently lacking in the market despite the facts that r-hGH was first approved for use by FDA in 1995, the conventional dosage form in the market has a […]
Coating electronics and performance materials requires assembling nanoparticles on targeted substrates such as polymers, ceramics, and metals. Many high-performance materials have hydrophobic or chemically inert surfaces. As a result, nanomaterial or particle coatings characteristically do not naturally stick to these surfaces, restricting their applications for aerospace, high altitude, battlefield, and other extreme environments. Currently, techniques […]
Fortune Business Insights reports that the global fungicide market size was valued at $17.1 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 4.93% to $25.81 billion by 2028. With the expansion of the global fungicide market, which includes manufacturing benzoxaboroles in large quantities, Dr. Tomsho’s protecting group […]
Chemical collections and methods for rapid storage, retrieval and assay are vital for new drug discovery. LIMR Chemical Genomics Center’s (LCGC) large chemical collection covers a unique structural space not covered by other pharma or commercial libraries. LCGC has developed a variety of hardware and software solutions to enable efficient, low-cost drug screens directed to […]