Lead Inventor Clyde M. Ofner III, Ph.D Unmet Need A major challenge in cancer chemotherapy is the selective delivery of small molecule anti-cancer agents to cancer cells. Doxorubicin (DOX) is a potent antineoplastic agent that is effective against a wide range of solid tumors and lymphomas but it is also associated with an irreversible cardiomyopathy […]
Life Sciences
A Drug Therapy Utilizing the Alpha4 / Beta2 Receptor Target for the Treatment of Obsessive-Compulsive
Unmet Need Phenylketonuria (PKU) is an inherited disorder that increases levels of phenylalanine in blood. Phenylalanine is an amino acid obtained through diet and found in all proteins and in some artificial sweeteners. If PKU is not treated, phenylalanine can build up to harmful levels in the body, causing intellectual disability and other serious health […]
A cell-based method to determine surface heterogeneity on polystyrene used in tissue culture flasks and dishes; increasing reliability of outcome of cell assays and reducing necessity to repeat cell-based tests.