Background and Unmet Need Chronic traumatic encephalopathy (CTE) is a progressive degenerative disease resulting from head trauma, particularly a history of repeated head trauma. Athletes who play contact sports and military personnel who incur repeated head traumas, including concussive or sub-concussive traumas, are at the greatest risk of developing CTE. Many athletes may experience […]
Issued Patent
Braftide is a synthetic peptide inhibitor that works via a novel dual mechanism of action to inhibit BRAF, a protein that is responsible for cell proliferation, differentiation, and migration. This protein is an integral part of the MAP kinase / ERK signaling pathway. Mutations in BRAF have been identified in melanoma, colorectal cancer, non-Hodgkins lymphoma, […]