Lankenau Institute for Medical Research scientists have developed a radically new approach to eradicate topical infections by weakening the local ecology of the infection that supports it. Specifically, they have developed topical over-the-counter (OTC) formulations of safe and effective agents that are capable of clearing recalcitrant topical infections such as onychomycosis, Staph, or plantar wart. […]
Drug Delivery & Wound Healing
Taking a radically new approach to eradicate topical infections, LIMR researchers have developed a set of topical over-the-counter (OTC) formulations of safe and effective agents. Their new approach is based on the concept of treating the infection ecology, which includes not only the microbial agent but also (1) the local supportive microbiome for the microbe, […]
Scars are an inescapable consequence of surgical wound healing because of normal processes of repair in mammals. For functional and cosmetic reasons, there is great interest in developing tools for non-scarring regeneration of normal tissue after a surgical procedure. While considerable effort has been dedicated to improving suturing and wound healing strategies that reduce scarring, […]
Hybrid molecular brushes (HMBs) are polymeric constructs comprising a backbone and ide chains of two or more polymers with varying properties. The overall molecular structure of HMBs is governed by steric repulsion among the side chains, and their grafting density on the backbone. HMBs with hydrophilic and hydrophobic fragments have recently come to the forefront, […]
When it comes to administration of recombinant human growth hormone (r-hGh), short half-life, instability in gastrointestinal tract, and low circulation time requiring frequent parenteral administration can lead to patient noncompliance. Researchers are investigating several polymer nanoparticle and micro particle based long acting delivery systems. However, comprehension of structural stability and polymer grade is fundamental for […]