Background and Unmet Need The US Congressional Water Authority reports that nitrogen is the main pollutant in rivers and streams, posing a significant threat to aquatic ecosystems and water quality nationwide. Although federal law currently does not limit nitrogen discharge from wastewater, 24 states have proactively implemented regulations to control nutrient levels and to […]
Pending Patent
Background Multispecific antibodies represent a paradigm shift in biotherapeutics, moving beyond the traditional “one target, one antibody” model of monoclonal antibodies (mAbs). By enabling a single therapeutic molecule to bind two or more distinct antigens or epitopes, multispecific antibodies can engage complex biological networks with a level of precision unattainable by monospecific mAbs. Among these, […]
Background and Unmet Need Per- and poly-fluoroalkyl (PFAS), also known as ‘Forever Chemicals,’ this class of chemicals has been a growing contaminant of concern throughout the last decade. PFAS present a significant human health risk, including an increased risk of cancer and reproductive defects. Because these chemicals are extremely hydrophobic and do not naturally break […]
Background and Unmet Need Legacy and insensitive high explosives (IHEs), such as 2,4-dinitroanisole (DNAN) and 2-methyl-1,3,5-trinitrobenzene (TN)T, are commonly found in soil at Department of Defense (DoD) testing and training ranges. These ranges maintain very high concentrations of DNAN, which poses a substantial safety concern for personnel as DNAN has been found to possess significant […]