Unmet Need Phenylketonuria (PKU) is an inherited disorder that increases levels of phenylalanine in the blood. Phenylalanine is an amino acid obtained through diet and found in all proteins and in some artificial sweeteners. If PKU is not treated, phenylalanine can build up to harmful levels in the body, causing intellectual disability and other serious health […]
Therapeutics & Prevention
Background and Unmet Need Chimeric Antigen Receptor T-cell therapy or CAR-T is a type of cancer immunotherapy that utilizes a patient’s own T cells that are genetically modified to recognize and attack cancer cells. This form of treatment has become massively popular as a customized solution to cancer therapies. While a new therapeutic area, […]
Unmet Need Serotonergic psychedelics like psilocybin and LSD are known to possess considerable therapeutic potential. They exhibit impressive clinical promise for the treatment of inflammatory disease, substance use disorders, psychiatric disorders, and various neurological conditions. However, there are significant challenges, as these drugs are limited by their hallucinogenic effects, which requires close clinical supervision and […]
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. AF patients exhibit increased risks for heart attacks, heart failure, hospitalization, and death. AF is increasing in prevalence, with up to 15.1M cases estimated annually by 2050 in the USA. This increase is in large part due to aging of the […]
Unmet Need Targeted and long-lasting formulations of chemotherapeutics with low doses and few side effects. Opportunity Simple formulations to delivery two or more therapeutics to cancers with similar pharmacokinetic profiles. Easier to manufacture than nano / micro particles. Good to use in combination with immune checkpoint inhibitors. Unique Attributes Apoptotic agent that acts independently of […]