Biotechnology

Small molecule allosteric agonists of glucagon-like peptide 1 receptor for treatment of type 2 diabetes

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The Glucagon-Like Peptide 1 Receptor (GLP-1R), a member of Class B family of G-protein coupled receptors (GPCRs), is an effective target for the treatment of type-2 diabetes, and its incretin peptide and varied peptide mimetics are adopted drugs. Despite remarkable anti-diabetic effects, GLP-1R peptide-based agonists are limited by several disadvantages. Although considerable progress has been […]

Microcapsules for Management of Phenylketonuria

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Unmet Need Phenylketonuria (PKU) is an inherited disorder that increases levels of phenylalanine in blood. Phenylalanine is an amino acid obtained through diet and found in all proteins and in some artificial sweeteners. If PKU is not treated, phenylalanine can build up to harmful levels in the body, causing intellectual disability and other serious health […]

Cell Based Method to Increase Heterogeneity

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A cell-based method to determine surface heterogeneity on polystyrene used in tissue culture flasks and dishes; increasing reliability of outcome of cell assays and reducing necessity to repeat cell-based tests.

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