Unmet Need Syntheses of phenethylamines in a rapid and efficient manner. Dr. Adejare’s demonstrated technology can save time, reagents, and number of steps in syntheses of arylalkylamines. The pharmaceutically relevant chemical classes include: phenylethylamines, alpha-alkylphenylethylamines, tryptamines, and arylcyclohexylamines. Opportunity Many fine chemicals, pharmaceutical products, and / or their intermediates can be synthesized using this technology. […]
Biotechnology
Human growth hormone (hGH), also known as somatotropin or somatropin, is a peptide hormone that stimulates growth and differentiation of target tissues. Exogenously administered hGH can be an effective treatment for growth disorders in both children and adults. It also is useful in treating catabolic disorders such as muscle wasting associated with acquired immunodeficiency syndrome […]
The Glucagon-Like Peptide 1 Receptor (GLP-1R), a member of Class B family of G-protein coupled receptors (GPCRs), is an effective target for the treatment of type-2 diabetes, and its incretin peptide and varied peptide mimetics are adopted drugs. Despite remarkable anti-diabetic effects, GLP-1R peptide-based agonists are limited by several disadvantages. Although considerable progress has been […]
LICENSED: Orally administered phenylalanine ammonia lyase microcapsules for the management of phenylketonuria (PKU).
A cell-based method to determine surface heterogeneity on polystyrene used in tissue culture flasks and dishes; increasing reliability of outcome of cell assays and reducing necessity to repeat cell-based tests.