Therapeutics & Prevention


Hybrid molecular brushes (HMBs) are polymeric constructs comprising a backbone and ide chains of two or more polymers with varying properties. The overall molecular structure of HMBs is governed by steric repulsion among the side chains, and their grafting density on the backbone. HMBs with hydrophilic and hydrophobic fragments have recently come to the forefront, […]

Braftide is a synthetic peptide inhibitor that works via a novel dual mechanism of action to inhibit BRAF, a protein that is responsible for cell proliferation, differentiation, and migration.  This protein is an integral part of the MAP kinase / ERK signaling pathway. Mutations in BRAF have been identified in melanoma, colorectal cancer, non-Hodgkins lymphoma, […]