St. Joseph's University


CAPER Peptides for the Treatment of Cancer

The University of the Sciences research team has uncovered CAPER as a novel therapeutic target inside breast cancer cells. CAPER has been shown to be overexpressed in these cancer cells and seems to be helping the cancer thrive and survive.  Targeted cancer therapy is becoming a leading approach to cancer treatment and Dr. Jasmin and […]

Stabilization of therapeutic protein on a polymer surface

When it comes to administration of recombinant human growth hormone (r-hGh), short half-life, instability in gastrointestinal tract, and low circulation time requiring frequent parenteral administration can lead to patient noncompliance. Researchers are investigating several polymer nanoparticle and micro particle based long acting delivery systems. However, comprehension of structural stability and polymer grade is fundamental for […]

Synthetic routes to phenethylamines, reducing pharma manufacturing cost

Unmet Need  Syntheses of phenethylamines in a rapid and efficient manner.  Dr. Adejare’s demonstrated technology can save time, reagents, and number of steps in syntheses of arylalkylamines.  The pharmaceutically relevant chemical classes include: phenylethylamines, alpha-alkylphenylethylamines, tryptamines, and arylcyclohexylamines. Opportunity  Many fine chemicals, pharmaceutical products, and / or their intermediates can be synthesized using this technology.  […]

Growth Hormone Delivery

Human growth hormone (hGH), also known as somatotropin or somatropin, is a peptide hormone that stimulates growth and differentiation of target tissues. Exogenously administered hGH can be an effective treatment for growth disorders in both children and adults. It also is useful in treating catabolic disorders such as muscle wasting associated with acquired immunodeficiency syndrome […]

Small molecule allosteric agonists of glucagon-like peptide 1 receptor for treatment of type 2 diabetes

The Glucagon-Like Peptide 1 Receptor (GLP-1R), a member of Class B family of G-protein coupled receptors (GPCRs), is an effective target for the treatment of type-2 diabetes, and its incretin peptide and varied peptide mimetics are adopted drugs. Despite remarkable anti-diabetic effects, GLP-1R peptide-based agonists are limited by several disadvantages. Although considerable progress has been […]