Targeted and long-lasting formulations of chemotherapeutics with low doses and few side effects. Simple formulations to delivery two or more therapeutics to cancers with similar pharmacokinetic profiles. Easier to manufacture than nano / micro particles. Good to use in combination with immune checkpoint inhibitors. Clinical Applications To sensitize the responses of cancers to chemotherapeutics. rHSA-p53 […]
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Chemical collections and methods for rapid storage, retrieval and assay are vital for new drug discovery. LIMR Chemical Genomics Center’s (LCGC) large chemical collection covers a unique structural space not covered by other pharma or commercial libraries. LCGC has developed a variety of hardware and software solutions to enable efficient, low-cost drug screens directed to […]
Burns are a major cause of serious soft tissue injury in the United States and around the world. Despite improvements in burn and bandage technology, burns remain a significant cause of hospitalization and death worldwide. In 2015, fire and heat resulted in 67 million injuries resulting about 2.9 million hospitalizations and 176,000 deaths worldwide[1]. The […]
Complex rotating machinery is an integral part of operations across multiple industries including healthcare, medical device, robotics, and traditional manufacturing. Turbomachinery, generators, engines, pumps, servo actuators, and electrical motors all depend on intricate inner mechanisms. Rotating machinery, such as turbomachinery, generators, motors, centrifuges, aircraft engines, pumps and fans, fail often because of bearing defects. Engines, […]
In industry, compressed air is so widely used that it is often regarded as the fourth utility after electricity, natural gas, and water. Compressed air energy storage (CAES) typically uses power from renewable energy (i.e., wind, solar) to compress air, and to generate electricity through a turbine when needed, as a way of (i) mitigating […]